New Approaches to Branched β-Amino α-Hydroxy Acids, Taxol Side-chain Analogs
نویسندگان
چکیده
The stereoselective synthesis of β -amino acids and their derivatives has been an active area of research, due to the importance of β -amino acids in various fields [1]. In particular, non-proteinogenic β -amino α-hydroxy acids are found in many natural products and drugs, for example N-benzoyl-3-phenylisoserine as a side-chain of taxol which has been approved for treatment of ovarian and breast cancer by the FDA [2] (Fig. 1).
منابع مشابه
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